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Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential

Semaphorin 4C (Sema4C) expression in human breast cancers correlates with poor disease outcome. Surprisingly, upon knock-down of Sema4C or its receptor PlexinB2 in diverse mammary carcinoma cells (but not their normal counterparts), we observed dramatic growth inhibition associated with impairment o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Gurrapu, Sreeharsha, Pupo, Emanuela, Franzolin, Giulia, Lanzetti, Letizia, Tamagnone, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030176/
https://ncbi.nlm.nih.gov/pubmed/29555978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0097-4
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