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Detection of the Cell Cycle-Regulated Negative Feedback Phosphorylation of Mitogen-Activated Protein Kinases in Breast Carcinoma using Nanofluidic Proteomics

Mitogen-activated protein kinases (MAPKs) play an important role in the regulation of cell proliferation, oncogenic transformation, and drug resistance. This study examined the capability of nanofluidic proteomics to identify aberrations in the MAPK signaling cascade, monitor its drug response, and...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Urasaki, Yasuyo, Fiscus, Ronald R., Le, Thuc T.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030070/
https://ncbi.nlm.nih.gov/pubmed/29968772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28335-8
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