Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers

INTRODUCTION: Mutations in the progranulin (GRN) gene are a major source of inherited frontotemporal degeneration (FTD) spectrum disorders associated with TDP-43 proteinopathy. We use structural MRI to identify regions of baseline differences and longitudinal changes in gray matter (GM) and white ma...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neuroimage Clin
Auteurs principaux: Olm, Christopher A., McMillan, Corey T., Irwin, David J., Van Deerlin, Vivianna M., Cook, Philip A., Gee, James C., Grossman, Murray
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029561/
https://ncbi.nlm.nih.gov/pubmed/29984158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.05.017
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