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Overcoming Therapeutic Resistance of Triple Positive Breast Cancer with CDK4/6 Inhibition
Triple positive breast cancers overexpress both the human epidermal growth factor receptor 2 (HER2) oncogene and the hormonal receptors (HR) to estrogen and progesterone. These cancers represent a unique therapeutic challenge because of a bidirectional cross-talk between the estrogen receptor alpha...
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Publicado no: | Int J Breast Cancer |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Hindawi
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6029445/ https://ncbi.nlm.nih.gov/pubmed/30018827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7835095 |
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