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Whole-exome sequencing identifies R1279X of MYH6 gene to be associated with congenital heart disease

BACKGROUND: Myosin VI, encoded by MYH6, is expressed dominantly in human cardiac atria and plays consequential roles in cardiac muscle contraction and comprising the cardiac muscle thick filament. It has been reported that the mutations in the MYH6 gene associated with sinus venosus atrial septal de...

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Bibliographic Details
Published in:BMC Cardiovasc Disord
Main Authors: Razmara, Ehsan, Garshasbi, Masoud
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029398/
https://ncbi.nlm.nih.gov/pubmed/29969989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-018-0867-4
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