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HapCHAT: adaptive haplotype assembly for efficiently leveraging high coverage in long reads

BACKGROUND: Haplotype assembly is the process of assigning the different alleles of the variants covered by mapped sequencing reads to the two haplotypes of the genome of a human individual. Long reads, which are nowadays cheaper to produce and more widely available than ever before, have been used...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Beretta, Stefano, Patterson, Murray D., Zaccaria, Simone, Della Vedova, Gianluca, Bonizzoni, Paola
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029272/
https://ncbi.nlm.nih.gov/pubmed/29970002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2253-8
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