Alzheimer Disease and Selected Risk Factors Disrupt a Co-regulation of Monoamine Oxidase-A/B in the Hippocampus, but Not in the Cortex

Monoamine oxidase-A (MAO-A) and MAO-B have both been implicated in the pathology of Alzheimer disease (AD). We examined 60 autopsied control and AD donor brain samples to determine how well MAO function aligned with two major risk factors for AD, namely sex and APOE ε4 status. MAO-A activity was inc...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Quartey, Maa O., Nyarko, Jennifer N. K., Pennington, Paul R., Heistad, Ryan M., Klassen, Paula C., Baker, Glen B., Mousseau, Darrell D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029266/
https://ncbi.nlm.nih.gov/pubmed/29997470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00419
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