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Prediction of RNA-protein sequence and structure binding preferences using deep convolutional and recurrent neural networks

BACKGROUND: RNA regulation is significantly dependent on its binding protein partner, known as the RNA-binding proteins (RBPs). Unfortunately, the binding preferences for most RBPs are still not well characterized. Interdependencies between sequence and secondary structure specificities is challengi...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Pan, Xiaoyong, Rijnbeek, Peter, Yan, Junchi, Shen, Hong-Bin
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029131/
https://ncbi.nlm.nih.gov/pubmed/29970003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4889-1
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