Residue-Specific Dynamics and Local Environmental Changes in Aβ40 Oligomer and Fibril Formation

Elucidating local dynamics of protein aggregation is crucial for understanding the mechanistic details of protein amyloidogenesis. Herein, we studied the residue-specific dynamics and local environmental changes of Ab40 along the course of aggregation by using para-cyanophenylalanine (Phe(CN)) as a...

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Publicado en:Angew Chem Int Ed Engl
Autores principales: Liu, Haiyang, Morris, Clifford, Lantz, Richard, Kent, Thomas W., Elbassal, Esmail A., Wojcikiewicz, Ewa P., Du, Deguo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028940/
https://ncbi.nlm.nih.gov/pubmed/29750857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201802490
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