Dynamics of RecA-mediated repair of replication-dependent DNA breaks

Chromosomal replication is the major source of spontaneous DNA double-strand breaks (DSBs) in living cells. Repair of these DSBs is essential for cell viability, and accuracy of repair is critical to avoid chromosomal rearrangements. Repair of replication-dependent DSBs occurs primarily by homologou...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Amarh, Vincent, White, Martin A., Leach, David R.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028544/
https://ncbi.nlm.nih.gov/pubmed/29789437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201803020
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