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Glutathione metabolism in cancer progression and treatment resistance

Glutathione (GSH) is the most abundant antioxidant found in living organisms and has multiple functions, most of which maintain cellular redox homeostasis. GSH preserves sufficient levels of cysteine and detoxifies xenobiotics while also conferring therapeutic resistance to cancer cells. However, GS...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Bansal, Ankita, Simon, M. Celeste
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028537/
https://ncbi.nlm.nih.gov/pubmed/29915025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804161
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