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Glutathione metabolism in cancer progression and treatment resistance

Glutathione (GSH) is the most abundant antioxidant found in living organisms and has multiple functions, most of which maintain cellular redox homeostasis. GSH preserves sufficient levels of cysteine and detoxifies xenobiotics while also conferring therapeutic resistance to cancer cells. However, GS...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Bansal, Ankita, Simon, M. Celeste
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028537/
https://ncbi.nlm.nih.gov/pubmed/29915025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804161
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