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Autoinhibition of kinesin-1 is essential to the dendrite-specific localization of Golgi outposts

Neuronal polarity relies on the selective localization of cargo to axons or dendrites. The molecular motor kinesin-1 moves cargo into axons but is also active in dendrites. This raises the question of how kinesin-1 activity is regulated to maintain the compartment-specific localization of cargo. Our...

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Vydáno v:J Cell Biol
Hlavní autoři: Kelliher, Michael T., Yue, Yang, Ng, Ashley, Kamiyama, Daichi, Huang, Bo, Verhey, Kristen J., Wildonger, Jill
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028532/
https://ncbi.nlm.nih.gov/pubmed/29728423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201708096
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