JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia

A substantial subset of patients with T cell acute lymphoblastic leukemia (T-ALL) develops resistance to steroids and succumbs to their disease. JDP2 encodes a bZIP protein that has been implicated as a T-ALL oncogene from insertional mutagenesis studies in mice, but its role in human T-ALL pathogen...

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Publicat a:J Exp Med
Autors principals: Mansour, Marc R., He, Shuning, Li, Zhaodong, Lobbardi, Riadh, Abraham, Brian J., Hug, Clemens, Rahman, Sunniyat, Leon, Theresa E., Kuang, You-Yi, Zimmerman, Mark W., Blonquist, Traci, Gjini, Evisa, Gutierrez, Alejandro, Tang, Qin, Garcia-Perez, Laura, Pike-Overzet, Karin, Anders, Lars, Berezovskaya, Alla, Zhou, Yi, Zon, Leonard I., Neuberg, Donna, Fielding, Adele K., Staal, Frank J.T., Langenau, David M., Sanda, Takaomi, Young, Richard A., Look, A. Thomas
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028512/
https://ncbi.nlm.nih.gov/pubmed/29941549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170484
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