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Itraconazole targets cell cycle heterogeneity in colorectal cancer
Cellular dormancy and heterogeneity in cell cycle length provide important explanations for treatment failure after adjuvant therapy with S-phase cytotoxics in colorectal cancer (CRC), yet the molecular control of the dormant versus cycling state remains unknown. We sought to understand the molecula...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028508/ https://ncbi.nlm.nih.gov/pubmed/29853607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171385 |
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