Genetic variants in systemic lupus erythematosus susceptibility loci, XKR6 and GLT1D1 are associated with childhood-onset SLE in a Korean cohort

Impact of genetic variants on the age of systemic lupus erythematosus (SLE) onset was not fully understood. We investigated a cumulative effect of SLE-risk variants on the age of SLE onset and scanned genome-wide SNPs to search for new risk loci of childhood-onset SLE (cSLE). We analyzed 781 Korean...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Joo, Young Bin, Lim, Jiwoo, Tsao, Betty P., Nath, Swapan K., Kim, Kwangwoo, Bae, Sang-Cheol
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028392/
https://ncbi.nlm.nih.gov/pubmed/29967481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28128-z
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