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Hermes Transposon Mutagenesis Shows [URE3] Prion Pathology Prevented by a Ubiquitin-Targeting Protein: Evidence for Carbon/Nitrogen Assimilation Cross Talk and a Second Function for Ure2p in Saccharomyces cerevisiae

[URE3] is an amyloid-based prion of Ure2p, a regulator of nitrogen catabolism. While most “variants” of the [URE3] prion are toxic, mild variants that only slightly slow growth are more widely studied. The existence of several antiprion systems suggests that some components may be protecting cells f...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Edskes, Herman K., Mukhamedova, Maryam, Edskes, Bouke K., Wickner, Reed B.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028256/
https://ncbi.nlm.nih.gov/pubmed/29769283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300981
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