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Signaling through Adenylyl Cyclase Is Essential for Hyphal Growth and Virulence in the Pathogenic Fungus Candida albicans

The human fungal pathogen Candida albicans switches from a budding yeast form to a polarized hyphal form in response to various external signals. This morphogenetic switching has been implicated in the development of pathogenicity. We have cloned the CaCDC35 gene encoding C. albicans adenylyl cyclas...

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Udgivet i:Mol Biol Cell
Principais autores: Rocha, Cintia R. C., Schröppel, Klaus, Harcus, Doreen, Marcil, Anne, Dignard, Daniel, Taylor, Brad N., Thomas, David Y., Whiteway, Malcolm, Leberer, Ekkehard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11694594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.11.3631
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