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In vivo expansion of functionally integrated GABAergic interneurons by targeted increase in neural progenitors

A central hypothesis for brain evolution is that it might occur via expansion of progenitor cells and subsequent lineage‐dependent formation of neural circuits. Here, we report in vivo amplification and functional integration of lineage‐specific circuitry in Drosophila. Levels of the cell fate deter...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Shaw, Rachel E, Kottler, Benjamin, Ludlow, Zoe N, Buhl, Edgar, Kim, Dongwook, Morais da Silva, Sara, Miedzik, Alina, Coum, Antoine, Hodge, James JL, Hirth, Frank, Sousa‐Nunes, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028031/
https://ncbi.nlm.nih.gov/pubmed/29728368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798163
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