miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking

Members of the miR‐200 family are critical gatekeepers of the epithelial state, restraining expression of pro‐mesenchymal genes that drive epithelial–mesenchymal transition (EMT) and contribute to metastatic cancer progression. Here, we show that miR‐200c and another epithelial‐enriched miRNA, miR‐3...

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Pubblicato in:EMBO J
Autori principali: Pillman, Katherine A, Phillips, Caroline A, Roslan, Suraya, Toubia, John, Dredge, B Kate, Bert, Andrew G, Lumb, Rachael, Neumann, Daniel P, Li, Xiaochun, Conn, Simon J, Liu, Dawei, Bracken, Cameron P, Lawrence, David M, Stylianou, Nataly, Schreiber, Andreas W, Tilley, Wayne D, Hollier, Brett G, Khew‐Goodall, Yeesim, Selth, Luke A, Goodall, Gregory J, Gregory, Philip A
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028027/
https://ncbi.nlm.nih.gov/pubmed/29871889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899016
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