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Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood–brain barrier
BACKGROUND: Dapoxetine (DPX) is the drug of choice for the specific treatment of premature ejaculation. DPX is characterized by relatively low bioavailability (42%) and short half-life (1.5 h). The aim of this study was to improve DPX bioavailability and delivery across the blood–brain barrier (BBB)...
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| 出版年: | Int J Nanomedicine |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6027843/ https://ncbi.nlm.nih.gov/pubmed/29983562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S168148 |
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