Electroporation-enhanced transdermal diclofenac sodium delivery into the knee joint in a rat model of acute arthritis

PURPOSE: Since electroporation (EP) can increase the permeability of biological membranes, we hypothesized that it offers an opportunity to enhance the transdermal delivery of drugs for intra-articular indications. Our aim was to compare the anti-inflammatory and analgesic efficacy of EP-combined to...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Hartmann, Petra, Butt, Edina, Fehér, Ágnes, Szilágyi, Ágnes Lilla, Jász, Kurszán Dávid, Balázs, Boglárka, Bakonyi, Mónika, Berkó, Szilvia, Erős, Gábor, Boros, Mihály, Horváth, Gyöngyi, Varga, Endre, Csányi, Erzsébet
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027698/
https://ncbi.nlm.nih.gov/pubmed/29983546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S161703
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