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Quantification of 6-Mercaptopurine and Its Metabolites in Patients with Acute Lympoblastic Leukemia Using Dried Blood Spots and UPLC-MS/MS

This research aimed to quantitatively bioanalyze 6-mercaptopurine (6-MP), 6-methylmercaptopurine (6-MMP), and 6-thioguanosine-5′-monophosphate (6-TGMP) in dried blood spots (DBS) prepared from a small volume of acute lymphoblastic leukemia (ALL) patients. Analytes on the DBS card were extracted usin...

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Publicado en:Sci Pharm
Main Authors: Supandi, Supandi, Harahap, Yahdiana, Harmita, Harmita, Andalusia, Rizka
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027686/
https://ncbi.nlm.nih.gov/pubmed/29693618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/scipharm86020018
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