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Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A ‘Chemobrain’ In Vitro Study

The potential neurotoxic effects of anticancer drugs, like doxorubicin (DOX) and mitoxantrone (MTX; also used in multiple sclerosis), are presently important reasons for concern, following epidemiological data indicating that cancer survivors submitted to chemotherapy may suffer cognitive deficits....

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Almeida, Daniela, Pinho, Rita, Correia, Verónica, Soares, Jorge, Bastos, Maria de Lourdes, Carvalho, Félix, Capela, João Paulo, Costa, Vera Marisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027466/
https://ncbi.nlm.nih.gov/pubmed/29734752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11020041
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