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Synthesis of Unsaturated Precursors for Parahydrogen-Induced Polarization and Molecular Imaging of 1-(13)C-Acetates and 1-(13)C-Pyruvates via Side Arm Hydrogenation
[Image: see text] Hyperpolarized forms of 1-(13)C-acetates and 1-(13)C-pyruvates are used as diagnostic contrast agents for molecular imaging of many diseases and disorders. Here, we report the synthetic preparation of 1-(13)C isotopically enriched and pure from solvent acetates and pyruvates deriva...
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| Veröffentlicht in: | ACS Omega |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2018
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026840/ https://ncbi.nlm.nih.gov/pubmed/29978146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00983 |
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