Metformin treatment ameliorates diabetes‐associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1

Age‐related reduction in adult hippocampal neurogenesis is correlated with cognitive impairment. Diabetes is a chronic systemic disease that negatively affects adult neural stem cells and memory functions in the hippocampus. Despite growing concern regarding the potential role of diabetic drugs in n...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Tanokashira, Daisuke, Kurata, Eiko, Fukuokaya, Wataru, Kawabe, Kenshiro, Kashiwada, Mana, Takeuchi, Hideyuki, Nakazato, Masamitsu, Taguchi, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026705/
https://ncbi.nlm.nih.gov/pubmed/29988567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12436
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