Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer

BACKGROUND: Some, but not all, epidemiologic evidence supports a role for cholesterol, the precursor for steroid hormone synthesis, in prostate cancer. Using a PTEN-null transgenic mouse model of prostate cancer, we tested the effect of modifying serum cholesterol levels on prostate tumor developmen...

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Détails bibliographiques
Publié dans:Prostate Cancer Prostatic Dis
Auteurs principaux: Allott, Emma H., Masko, Elizabeth M., Freedland, Alexis R., Macias, Everardo, Pelton, Kristine, Solomon, Keith R., Mostaghel, Elahe A., Thomas, George V., Pizzo, Salvatore V., Freeman, Michael R., Freedland, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026483/
https://ncbi.nlm.nih.gov/pubmed/29795142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-018-0045-x
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