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Novel Modulators of Proteostasis: RNAi Screen of Chromosome I in a Heat Stress Paradigm in C. elegans

Proteostasis is of vital importance for cellular function and it is challenged upon exposure to acute or chronic insults during neurodegeneration and aging. The proteostasis network is relevant for the maintenance of proteome integrity and mainly comprises molecular chaperones and two degradation pa...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Kern, Andreas, Spang, Natalie, Huesmann, Heike, Behl, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025327/
https://ncbi.nlm.nih.gov/pubmed/29861461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7060049
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