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Using Fragment-Based Approaches to Discover New Antibiotics

Fragment-based lead discovery has emerged over the past two decades as a successful approach to generate novel lead candidates in drug discovery programs. The two main advantages over conventional high-throughput screening (HTS) are more efficient sampling of chemical space and tighter control over...

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Podrobná bibliografie
Vydáno v:SLAS Discov
Hlavní autoři: Lamoree, Bas, Hubbard, Roderick E.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024353/
https://ncbi.nlm.nih.gov/pubmed/29923463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218773034
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