Anti-Allergic Inflammatory Activity of Interleukin-37 Is Mediated by Novel Signaling Cascades in Human Eosinophils

IL-1 family regulatory cytokine IL-37b can suppress innate immunity and inflammatory activity in inflammatory diseases. In this study, IL-37b showed remarkable in vitro suppression of inflammatory tumor necrosis factor-α, IL-1β, IL-6, CCL2, and CXCL8 production in the coculture of human primary eosi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhu, Jing, Dong, Jie, Ji, Lu, Jiang, Peiyong, Leung, Ting Fan, Liu, Dehua, Ng, Lai Guan, Tsang, Miranda Sin-Man, Jiao, Delong, Lam, Christopher Wai-Kei, Wong, Chun-Kwok
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023969/
https://ncbi.nlm.nih.gov/pubmed/29988381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01445
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