Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4

Dendritic cell (DC)-based immunotherapy makes use of the DC’s ability to direct the adaptive immune response toward activation or inhibition. DCs perform this immune orchestration in part by secretion of selected cytokines. The most potent anti-inflammatory cytokine interleukin-10 (IL-10) is under t...

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Vydáno v:Front Immunol
Hlavní autoři: Søndergaard, Jonas Nørskov, van Heeringen, Simon J., Looman, Maaike W. G., Tang, Chunling, Triantis, Vassilis, Louche, Pauline, Janssen-Megens, Eva M., Sieuwerts, Anieta M., Martens, John W. M., Logie, Colin, Stunnenberg, Hendrik G., Ansems, Marleen, Adema, Gosse J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023963/
https://ncbi.nlm.nih.gov/pubmed/29988341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01420
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