Role of striatal direct pathway 2-arachidonoylglycerol signaling in sociability and repetitive behavior

BACKGROUND: Endocannabinoid signaling plays an important role in regulating synaptic transmission in the striatum, a brain region implicated as a central node of dysfunction in autism spectrum disorder (ASD). Deficits in signaling mediated by the endocannabinoid 2-arachidonoyl glycerol (2-AG) have b...

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Bibliographic Details
Published in:Biol Psychiatry
Main Authors: Shonesy, Brian C., Parrish, Walker P., Haddad, Hala K., Stephenson, Jason R., Báldi, Rita, Bluett, Rebecca J., Marks, Christian R., Centanni, Samuel W., Folkes, Oakleigh M., Spiess, Keeley, Augustin, Shana M., Mackie, Ken, Lovinger, David M., Winder, Danny G., Patel, Sachin, Colbran, Roger J.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023784/
https://ncbi.nlm.nih.gov/pubmed/29458998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.11.036
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