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Hypoxia Supports Epicardial Cell Differentiation in Vascular Smooth Muscle Cells through the Activation of the TGFβ Pathway

Epicardium-derived cells (EPDCs) are an important pool of multipotent cardiovascular progenitor cells. Through epithelial-to-mesenchymal-transition (EMT), EPDCs invade the subepicardium and myocardium and further differentiate into several cell types required for coronary vessel formation. We previo...

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Bibliografiske detaljer
Udgivet i:J Cardiovasc Dev Dis
Main Authors: Tao, Jiayi, Barnett, Joey V., Watanabe, Michiko, Ramírez-Bergeron, Diana
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023394/
https://ncbi.nlm.nih.gov/pubmed/29652803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcdd5020019
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