SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes

Small integral membrane protein of the lysosome/late endosome (SIMPLE) is a 161-amino acid cellular protein that contains a characteristic C-terminal domain known as the SIMPLE-like domain (SLD), which is well conserved among species. Several studies have demonstrated that SIMPLE localizes to the tr...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Moriwaki, Yasuhiro, Ohno, Yuho, Ishii, Tomohiro, Takamura, Yuki, Kita, Yuko, Watabe, Kazuhiko, Sango, Kazunori, Tsuji, Shoutaro, Misawa, Hidemi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023223/
https://ncbi.nlm.nih.gov/pubmed/29953492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199829
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