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Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly
TOR is a serine/threonine protein kinase that assembles into distinct TOR Complexes 1 and 2 (TORC1 or TORC2) to regulate cell growth. In mammalian cells, a single mTOR incorporates stably into mTORC1 and mTORC2. By contrast, in Saccharomyces cerevisiae, two highly similar Tor1 and Tor2 proteins exis...
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| Publicado en: | Biomolecules |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023025/ https://ncbi.nlm.nih.gov/pubmed/29865216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8020036 |
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