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Redesigning TOR Kinase to Explore the Structural Basis for TORC1 and TORC2 Assembly

TOR is a serine/threonine protein kinase that assembles into distinct TOR Complexes 1 and 2 (TORC1 or TORC2) to regulate cell growth. In mammalian cells, a single mTOR incorporates stably into mTORC1 and mTORC2. By contrast, in Saccharomyces cerevisiae, two highly similar Tor1 and Tor2 proteins exis...

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Bibliografiset tiedot
Julkaisussa:Biomolecules
Päätekijät: Hill, Andrew, Niles, Brad, Cuyegkeng, Andrew, Powers, Ted
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023025/
https://ncbi.nlm.nih.gov/pubmed/29865216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8020036
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