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Protein Turnover in Aging and Longevity

Progressive loss of proteostasis is a hallmark of aging that is marked by declines in various components of proteostasis machinery, including: autophagy, ubiquitin‐mediated degradation, protein synthesis, and others. While declines in proteostasis have historically been observed as changes in these...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Basisty, Nathan, Meyer, Jesse G., Schilling, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022828/
https://ncbi.nlm.nih.gov/pubmed/29453826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700108
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