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Phase separation drives heterochromatin domain formation

Constitutive heterochromatin is an important component of eukaryotic genomes that has essential roles in nuclear architecture, DNA repair and genome stability(1), and silencing of transposon and gene expression(2). Heterochromatin is highly enriched for repetitive sequences, and is defined epigeneti...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Strom, Amy R., Emelyanov, Alexander V., Mir, Mustafa, Fyodorov, Dmitry V., Darzacq, Xavier, Karpen, Gary H.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022742/
https://ncbi.nlm.nih.gov/pubmed/28636597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22989
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