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Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury

Dendrite pathology and synapse disassembly are critical features of chronic neurodegenerative diseases. In spite of this, the capacity of injured neurons to regenerate dendrites has been largely ignored. Here, we show that, upon axonal injury, retinal ganglion cells undergo rapid dendritic retractio...

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Bibliografiske detaljer
Udgivet i:Brain
Main Authors: Agostinone, Jessica, Alarcon-Martinez, Luis, Gamlin, Clare, Yu, Wan-Qing, Wong, Rachel O L, Di Polo, Adriana
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022605/
https://ncbi.nlm.nih.gov/pubmed/29931057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy142
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