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CrossPlan: systematic planning of genetic crosses to validate mathematical models

MOTIVATION: Mathematical models of cellular processes can systematically predict the phenotypes of novel combinations of multi-gene mutations. Searching for informative predictions and prioritizing them for experimental validation is challenging since the number of possible combinations grows expone...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Pratapa, Aditya, Adames, Neil, Kraikivski, Pavel, Franzese, Nicholas, Tyson, John J, Peccoud, Jean, Murali, T M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022539/
https://ncbi.nlm.nih.gov/pubmed/29432533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty072
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