Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via direct mitochondria-to-nucleus translocation

As most of the mitochondrial proteome is encoded in the nucleus, mitochondrial functions critically depend on nuclear gene expression and bidirectional mito-nuclear communication. However, mitochondria-to-nucleus communication pathways in mammals are incompletely understood. Here, we identify G-Prot...

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Publicado no:Mol Cell
Main Authors: Cardamone, Maria Dafne, Tanasa, Bogdan, Cederquist, Carly T., Huang, Jiawen, Mahdaviani, Kiana, Li, Wenbo, Rosenfeld, Michael G., Liesa, Marc, Perissi, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022402/
https://ncbi.nlm.nih.gov/pubmed/29499132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.037
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