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ClC-2 knockdown prevents cerebrovascular remodeling via inhibition of the Wnt/β-catenin signaling pathway

BACKGROUND: Mishandling of intracellular chloride (Cl(−)) concentration ([Cl(−)](i)) in cerebrovascular smooth muscle cells is implicated in several pathological processes, including hyperplasia and remodeling. We investigated the effects of ClC-2-mediated Cl(−) efflux on the proliferation of human...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Lu, Jingjing, Xu, Feng, Zhang, Yingna, Lu, Hong, Zhang, Jiewen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022329/
https://ncbi.nlm.nih.gov/pubmed/29988306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0095-z
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