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Enantioselective synthesis of Iboga alkaloids and vinblastine via rearrangements of quaternary ammoniums

An efficient and novel strategy for the enantioselective syntheses of various iboga alkaloids has been developed. The salient features include a gold-catalyzed oxidation of a terminal alkyne followed by cyclization, a Stevens rearrangement and a tandem sequence that combines the gold-catalyzed oxida...

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Vydáno v:Chem Sci
Hlavní autoři: Zhang, Yun, Xue, Yibin, Li, Gang, Yuan, Haosen, Luo, Tuoping
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021789/
https://ncbi.nlm.nih.gov/pubmed/30034694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00932h
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