Pharmacokinetic Changes during Pregnancy According to Genetic Variants: a Prospective Study in HIV-Infected Patients Receiving Atazanavir-Ritonavir

Atazanavir-ritonavir concentrations change over time during pregnancy in HIV-positive patients; the impact of genetic variants is unknown. Twenty patients were enrolled in this study; plasma and intracellular concentrations of antiretrovirals were measured, in addition to single-nucleotide polymorph...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Focà, Emanuele, Calcagno, Andrea, Bonito, Andrea, Cusato, Jessica, Domenighini, Elisabetta, D'Avolio, Antonio, Quiros Roldan, Eugenia, Trentini, Laura, Castelnuovo, Filippo, Di Perri, Giovanni, Castelli, Francesco, Bonora, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021630/
https://ncbi.nlm.nih.gov/pubmed/29760129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00309-18
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