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CRISPR/Cas9-mediated knock-in of the murine Y chromosomal Sry gene
Mammalian zygote-mediated genome editing via the clustered regularly interspaced short palindromic repeats/CRISPR-associated endonuclease 9 (CRISPR/Cas9) system is widely used to generate genome-modified animals. This system allows for the production of loss-of-function mutations in various Y chromo...
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| Veröffentlicht in: | J Reprod Dev |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Society for Reproduction and Development
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021606/ https://ncbi.nlm.nih.gov/pubmed/29657232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2017-161 |
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