Mitochondrial dysfunction in cumulus-oocyte complexes increases cell-free mitochondrial DNA

This study examined the concentration of cell-free mitochondrial DNA (cf-mtDNA) in porcine follicular fluid (FF) and explored whether the cfDNA level in the culture medium could reflect mitochondrial dysfunction in cumulus cell-oocyte complexes (COCs). cfDNA concentration was higher in the fluid of...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: KANSAKU, Kazuki, MUNAKATA, Yasuhisa, ITAMI, Nobuhiko, SHIRASUNA, Koumei, KUWAYAMA, Takehito, IWATA, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021605/
https://ncbi.nlm.nih.gov/pubmed/29618676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2018-012
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