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The 1.19 Å X-ray structure of 2′-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove

The crystal and molecular structure of 2′-O-Me(CGCGCG)(2) has been determined at 1.19 Å resolution, at 100 K, using synchrotron radiation. The structure in space group P3(2)12 is a half-turn right-handed helix that includes two 2-methyl-2,4-pentanediol (MPD) molecules bound in the minor groove. The...

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Hlavní autoři: Adamiak, Dorota A., Rypniewski, Wojciech R., Milecki, Jan, Adamiak, Ryszard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC60216/
https://ncbi.nlm.nih.gov/pubmed/11600703
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