Dephosphorylated Polymerase I and Transcript Release Factor Prevents Allergic Asthma Exacerbations by Limiting IL-33 Release

BACKGROUND: Asthma is a chronic inflammatory disease characterized by airway inflammation and airway hyperresponsiveness (AHR). IL-33 is considered as one of the most critical molecules in asthma pathogenesis. IL-33 is stored in nucleus and passively released during necrosis. But little is known abo...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ni, Yingmeng, Hao, Jimin, Hou, Xiaoxia, Du, Wei, Yu, Youchao, Chen, Tiantian, Wei, Zhuang, Li, Yangyang, Zhu, Fuxiang, Wang, Shuaiwei, Liang, Rui, Li, Dan, Lu, Yue, Liao, Kan, Li, Bin, Shi, Guochao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021487/
https://ncbi.nlm.nih.gov/pubmed/29977243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01422
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