Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4

Middle East respiratory syndrome (MERS) represents an important respiratory disease accompanied by lethal outcome in one-third of human patients. Recent data indicate that dromedaries represent an important source of infection, although information regarding viral cell tropism and pathogenesis is sp...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Haverkamp, Ann-Kathrin, Lehmbecker, Annika, Spitzbarth, Ingo, Widagdo, Widagdo, Haagmans, Bart L., Segalés, Joaquim, Vergara-Alert, Julia, Bensaid, Albert, van den Brand, Judith M. A., Osterhaus, Albert D. M. E., Baumgärtner, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021449/
https://ncbi.nlm.nih.gov/pubmed/29950581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28109-2
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