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Gp41 dynamically interacts with the TCR in the immune synapse and promotes early T cell activation

The HIV-1 glycoprotein gp41 critically mediates CD4(+) T-cell infection by HIV-1 during viral entry, assembly, and release. Although multiple immune-regulatory activities of gp41 have been reported, the underlying mechanisms of these activities remain poorly understood. Here we employed multi-colour...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yakovian, Oren, Schwarzer, Roland, Sajman, Julia, Neve-Oz, Yair, Razvag, Yair, Herrmann, Andreas, Sherman, Eilon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021400/
https://ncbi.nlm.nih.gov/pubmed/29950577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28114-5
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