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Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome

Fragile X syndrome (FXS) is the most prevalent inherited intellectual disability, resulting from a loss of fragile X mental retardation protein (FMRP). Patients with FXS suffer lifelong cognitive disabilities, but the function of FMRP in the adult brain and the mechanism underlying age-related cogni...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Li, Yue, Stockton, Michael E., Eisinger, Brian E., Zhao, Yinghua, Miller, Jessica L., Bhuiyan, Ismat, Gao, Yu, Wu, Zhiping, Peng, Junmin, Zhao, Xinyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021376/
https://ncbi.nlm.nih.gov/pubmed/29950602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04869-3
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