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T-cell immunopeptidomes reveal cell subtype surface markers derived from intracellular proteins

Immunopeptidomes promise novel surface markers as ideal immunotherapy targets, but their characterization by mass spectrometry (MS) remains challenging. Until recently, cell numbers exceeding 10(9) were needed to survey thousands of HLA ligands. Such limited analytical sensitivity has historically c...

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Dades bibliogràfiques
Publicat a:Proteomics
Autors principals: Olsson, Niclas, Schultz, Liora M, Zhang, Lichao, Khodadoust, Michael S., Narayan, Rupa, Czerwinski, Debra K., Levy, Ronald, Elias, Joshua E.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021197/
https://ncbi.nlm.nih.gov/pubmed/29493099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700410
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